BioNTech doses first patient in herpes vaccine candidate clinical ... - PharmaLive

BioNTech doses first patient in herpes vaccine candidate clinical trial

Dec 21 (Reuters) – BioNtech (22UAy.DE) has dosed the first patient with its BNT163 herpes vaccine candidate designed to prevent genital lesions as part of a first-in-human Phase 1 clinical research study, the German vaccine maker said on Wednesday.

The vaccine candidate is meant to prevent HSV-2, the herpes simplex virus that causes genital herpes, and potentially HSV-1, which causes oral herpes and can lead to genital herpes.

It is the first result of the research collaboration established in 2018 between the University of Pennsylvania and BioNTech aimed at developing novel mRNA vaccine candidates for the prevention and treatment of various infectious diseases.

The World Health Organization estimates the number of people aged 15-49 suffering from HSV-2 infection at around 491 million.

BioNTech expects to enroll 100 people between ages 18 and 55 for its Phase 1 trial of the drug, the firm added.

The Mainz-based firm said in a separate news release that it is advancing two mRNA vaccine candidates for malaria and tuberculosis, which it expects to enter first-in-human trials in late 2022 or early 2023.

Reporting by Tristan Chabba in Gdansk Editing by Miranda Murray

Our Standards: The Thomson Reuters Trust Principles.

Source: Reuters

Comments

Post a Comment

Popular posts from this blog

Effect of a board game on imprisoned women's knowledge about ... - BMC Public Health

Image
The Previna board game was designed to be a complementary tool in the teaching and learning process about STIs for imprisoned women. The results showed that this educational technology significantly increased the players' knowledge about STIs and that this increase in knowledge remained significant during follow-up. This suggests that there was knowledge retention in the period researched. The increase in knowledge was also present in other studies that used board games for educational purposes [13,14,15,16]. The knowledge retention observed in this study is a result that draws attention, as the school teachers frequently mentioned that the women had difficulty retaining the contents taught in the classroom. This suggests that the approach to content may or may not favor this process. In this way, the board game can be used to present educational content to adult students in order to address their learning needs [14] and to make learning more significant and engaging. Regardless of...
Read more

Herpes Simplex: Two Types, Comparison Chart, Prevention - Verywell Health

Image
Herpes is a viral infection transmitted through skin contact. The two most common strains, herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2), cause oral herpes (cold sores) and genital herpes infections. Between 50% and 80% of people in the United States have HSV-1, and almost 12% of people between the ages of 14 and 49 have an HSV-2 infection. Read on for more information on both herpes simplex viruses, including transmission, symptoms, diagnosis, and treatment. belchonock / Getty Images Types of Herpes Simplex There are two types of HSV strains: HSV-1 : This strain typically causes an oral herpes infection but can cause symptoms in the genital area if that is where the virus was transmitted. HSV-2 : This virus strain typically causes symptoms in the genital and anal area. It may also cause an infection in or around the mouth. While each strain does commonly cause an infection on a particular part of the body, it is possible fo...
Read more

The 5 Best OTC Cold Sore Treatments of 2024 - Health.com

Image
Cold sores are quite common, and many people have a cold sore outbreak a few times a year. Itchy, painful, irritated, and sensitive cold sores are caused by the herpes simplex virus type 1 (HSV-1) and, less commonly, HSV 2. According to the World Health Organization, an estimated 3.7 billion people globally have an HSV-1 infection at a given time, which is the main cause of cold sores. Most cold sores go away within a few weeks without treatment. However, multiple over-the-counter (OTC) ways to treat cold sores can help speed healing without needing to see a healthcare provider. Many people use oral treatments for prevention or treatment, explains Allison K. Truong, MD, a board-certified dermatologist in Beverly Hills, CA. These can reduce symptoms to seven days or prevent the cold sore from forming if you catch it early enough. We surveyed 28 participants to find out which OTC cold sore treatment they tried, how effective it was, and why they liked it. The below over-the-c...
Read more