INOVIO to Report First Quarter 2020 Financial Results on May 11, 2020 - The Wellsboro Gazette

INOVIO to Report First Quarter 2020 Financial Results on May 11, 2020 - The Wellsboro Gazette

INOVIO to Report First Quarter 2020 Financial Results on May 11, 2020 - The Wellsboro Gazette

Posted: 27 Apr 2020 05:25 AM PDT

PLYMOUTH MEETING, Pa., April 27, 2020 /PRNewswire/ -- INOVIO (NASDAQ:INO) announced today that first quarter 2020 financial results will be released after the market close on May 11, 2020. Following the release, the Company will host a live conference call and webcast at 4:30 p.m. ET to discuss financial results and provide a general business update, including the company's ongoing vaccine developments for COVID-19.

A live and archived version of the audio presentation will be available online at http://ir.inovio.com/investors/events/default.aspx. This is a listen-only event but will include a live Q&A with analysts.

Telephone replay will be available approximately one hour after the call at 877-344-7529 (US toll free) or 412-317-0088 (international toll) using replay access code 10143530.

About INOVIO

INOVIO is a biotechnology company focused on rapidly bringing to market precisely designed DNA medicines to potentially treat and protect people from diseases associated with HPV, cancer, and infectious diseases. INOVIO is the first and only company to have clinically demonstrated that a DNA medicine can be delivered directly into cells in the body via a proprietary smart device to produce a robust and tolerable immune response. Specifically, INOVIO's lead candidate VGX-3100, currently in Phase 3 trials for precancerous cervical dysplasia, destroyed and cleared high-risk HPV 16 and 18 in a Phase 2b clinical trial. High-risk HPV is responsible for 70% of cervical cancer, 91% of anal cancer, and 69% of vulvar cancer. Also in development are programs targeting HPV-related cancers and a rare HPV-related disease, recurrent respiratory papillomatosis (RRP); non-HPV-related cancers glioblastoma multiforme (GBM) and prostate cancer; as well as externally funded infectious disease DNA vaccine development programs in Zika, Lassa fever, Ebola, HIV, and coronaviruses associated with MERS and COVID-19 diseases. Partners and collaborators include Advaccine, ApolloBio Corporation, AstraZeneca, The Bill & Melinda Gates Foundation, Coalition for Epidemic Preparedness Innovations (CEPI), Defense Advanced Research Projects Agency (DARPA)/Department of Defense (DOD), GeneOne Life Science/VGXI, HIV Vaccines Trial Network, International Vaccine Institute (IVI), Medical CBRN Defense Consortium (MCDC), National Cancer Institute, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Ology Bioservices, Plumbline Life Sciences, Regeneron, Richter-Helm, Roche/Genentech, University of Pennsylvania, Walter Reed Army Institute of Research, and The Wistar Institute. INOVIO also is a proud recipient of 2020 Women on Boards "W" designation recognizing companies with more than 20% women on their board of directors. For more information, visit www.inovio.com.

CONTACTS:                                                                                                                            

Investors:          Ben Matone, 484-362-0076, ben.matone@inovio.com
Media:              Jeff Richardson, 267-440-4211, jrichardson@inovio.com

This press release contains certain forward-looking statements relating to INOVIO's business, including our plans to develop DNA medicines, our expectations regarding our research and development programs, as well as commercialization activities, including the planned initiation and conduct of clinical trials, the availability and timing of data from those trials and our commercialization strategy and tactics. Actual events or results may differ from the expectations set forth herein as a result of a number of factors, including uncertainties inherent in preclinical studies, clinical trials, product development programs and commercialization activities and outcomes, the availability of funding to support continuing research and studies in an effort to prove safety and efficacy of electroporation technology as a delivery mechanism or develop viable DNA medicines, our ability to support our pipeline of DNA medicine products, the ability of our collaborators to attain development and commercial milestones for products we license and product sales that will enable us to receive future payments and royalties, the adequacy of our capital resources, the availability or potential availability of alternative therapies or treatments for the conditions targeted by us or our collaborators, including alternatives that may be more efficacious or cost effective than any therapy or treatment that we and our collaborators hope to develop, issues involving product liability, issues involving patents and whether they or licenses to them will provide us with meaningful protection from others using the covered technologies, whether such proprietary rights are enforceable or defensible or infringe or allegedly infringe on rights of others or can withstand claims of invalidity and whether we can finance or devote other significant resources that may be necessary to prosecute, protect or defend them, the level of corporate expenditures, assessments of our technology by potential corporate or other partners or collaborators, capital market conditions, the impact of government healthcare proposals and other factors set forth in our Annual Report on Form 10-K for the year ended December 31, 2019, and other filings we make from time to time with the Securities and Exchange Commission. There can be no assurance that any product candidate in our pipeline will be successfully developed, manufactured or commercialized, that final results of clinical trials will be supportive of regulatory approvals required to market products, or that any of the forward-looking information provided herein will be proven accurate. Forward-looking statements speak only as of the date of this release, and we undertake no obligation to update or revise these statements, except as may be required by law.

China Focus: Chinese HPV vaccine to be available in May - Xinhua | English.news.cn - Xinhua

Posted: 26 Apr 2020 12:43 AM PDT

XIAMEN, April 26 (Xinhua) -- In a major step forward in fighting cervical cancer, a human papillomavirus (HPV) vaccine developed by Chinese researchers will be widely available in the country for women under the age of 45 in May.

The HPV vaccine was jointly developed by Xiamen University and a subsidiary of YangShengTang Group in east China's Fujian Province, after an 18-year study. It was approved by the National Medical Products Administration in December 2019.

Starting next month, the first batch of more than 93,000 vaccines will be available in community hospitals in provincial-level regions including Hubei, Jilin and Xinjiang Uygur Autonomous Region, said a source of the university Sunday.

Cervical cancer is caused by sexually acquired infection with certain types of HPV. It is the third most common cancer among women.

China has a very high incidence and death rate, and previous studies show that for Chinese women the peak incidence of HPV infection occurs between the ages of 15 and 19.

The World Health Organization (WHO) and many countries recommend people to get vaccinated between the ages of 9 through 14.

The newly available vaccine can protect against HPV 16 and 18, two major HPV types causing 70 percent of all cervical cancers. It can be given to women aged 9 to 45, according to the source.

British pharmaceutical giant GlaxoSmithKline's Cervarix is the first HPV vaccine introduced in China and the current market-available HPV vaccine with the same type of coverage. Both vaccines require three shots over six months, but the Chinese vaccine is cheaper, with one shot priced at 329 yuan (about 46.5 U.S. dollars). One shot of Cervarix meanwhile is priced at 580 yuan in the Chinese market.

"Many cervical cancer patients are on low incomes," said Sui Long, a chief gynecologist at the Obstetrics and Gynecology Hospital affiliated to Fudan University in Shanghai, adding that the domestically produced vaccine will make the vaccination affordable for many poor patients.

Due to safety concerns, many vaccines were not available on the Chinese mainland until Cervarix was approved in July 2016. Mainland residents had to travel to Hong Kong or abroad to get the three-shot vaccination, making the cost higher.

FURTHER EFFORTS

In May 2018, the WHO called on all countries to take action to eliminate cervical cancer globally by 2030. China has been stepping up efforts in promoting and developing HPV vaccines in recent years.

Another HPV vaccine developed by Xiamen University covering nine HPV types will undergo a phase three clinical trial, the last test before reaching the market, the university source noted.

Last year, the university announced that it had made a breakthrough in developing a new-generation vaccine that has the potential to protect against almost all of the most lethal HPV forms. In September 2019, the university, with the YangShengTang Group, signed an agreement with GlaxoSmithKline to work on developing the next-generation HPV vaccine together.

The university has rich experiences in vaccine research. It also received a donation worth 600,000 U.S. dollars from the Bill & Melinda Gates Foundation in March for supporting COVID-19 diagnostic reagents and vaccine development.

A lack of public awareness is another obstacle in China. Previous studies show that only 15 percent of women on the Chinese mainland have heard of the vaccines, said Sui.

Gong Xiaoming, a leading Chinese gynecologist in Beijing with thousands of followers online, has been promoting the HPV vaccination on social media since 2014. He said it is effective and advises all people to get it, the earlier the better, as the virus is primarily transmitted through sexual contact.

Women can also prevent the disease through regular health checks, he said. From 2009 to 2016, China offered free cervical cancer checks to more than 60 million rural women.

"Cervical cancer is potentially fatal but preventable," said Gong. "It's essential we raise public awareness of the disease and the vaccine benefits." Enditem

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