Posts

Assessment of malignant potential for HPV types 16, 52, and 58 in the uterine cervix within a Korean cohort | Scientific ... - Nature.com

Image
Abstract High-risk human papillomavirus (HR-HPV) is the primary carcinogen in uterine cervical carcinoma. While genotype-specific carcinogenic risks have been extensively studied in Western populations, data from Korean are sparse. This study evaluates the malignant potential of the three most prevalent HR-HPVs in Korea: HPV16, HPV52, and HPV58. We analyzed 230 patients who underwent cervical conization and had been tested for HPV within a year prior to the procedure, excluding those with multiple infections. This analysis was confined to patients with single HPV infections and assessed outcomes of CIN3+, which includes carcinoma in situ (CIN3) and invasive carcinoma. The incidence of invasive cervical cancer was 6.7% for HPV16, 1.7% for HPV52, and 2.0% for HPV58; however, these differences were not statistically significant ( p  = 0.187). The rate of CIN3+ for HPV16, HPV52, and HPV58 were 70.6%, 51.7%, and 58.8%, respectively. Despite the small sample size, which may limit the robustn

How Common Are Cold Sores (Fever Blisters) During Pregnancy? - MomJunction

Image
Image: Shutterstock Cold sores or fever blisters erupt inside the lips or cheeks, around the mouth, or near the nose and chin. These itchy and tingly sores might sometimes be painful too. Usually, cold sores are likely to disappear in a couple of weeks. But what happens when they occur during pregnancy? What should you do about them? We tell you about it in this MomJunction post. Keep reading to know more about cold sores during pregnancy. Are Cold Sores Common In Pregnancy? Cold sores are usually caused by herpes simplex virus i A type of virus that affects the genital, anal area, or mouth (HSV), especially type 1 of the virus (1). Therefore, they are likely to be common in women who have experienced them in the past (2). What Are The Causes Of Cold Sores During Pre

Pediatric Herpes Simplex Virus Infection: Practice Essentials, Background, Pathophysiology - Medscape Reference

Arduino PG, Porter SR. Herpes Simplex Virus Type 1 infection: overview on relevant clinico-pathological features. J Oral Pathol Med . 2008 Feb. 37(2):107-21. [QxMD MEDLINE Link]. Johnston C, Magaret A, Selke S, Remington M, Corey L, Wald A. Herpes simplex virus viremia during primary genital infection. J Infect Dis . 2008 Jul 1. 198(1):31-4. [QxMD MEDLINE Link]. Kimberlin DW. Herpes simplex virus infections in neonates and early childhood. Semin Pediatr Infect Dis . 2005 Oct. 16(4):271-81. [QxMD MEDLINE Link]. Kimberlin DW. Herpes simplex virus infections of the newborn. Semin Perinatol . 2007 Feb. 31(1):19-25. [QxMD MEDLINE Link]. Kimberlin DW, Whitley RJ. Neonatal herpes: what have we learned. Semin Pediatr Infect Dis . 2005 Jan. 16(1):7-16. [QxMD MEDLINE Link]. Kimberlin D. Herpes simplex virus, meningitis and encephalitis in neonates. Herpes . 2004 Jun. 11 Suppl 2:65A-76A. [QxMD MEDLINE Link]. Jacobs RF. Neonatal herpes si